Two Popular Classes of Drugs Linked to Higher Dementia Risk and Memory Problems, Possible Alternatives

Anticholinergics: Linked to higher dementia risk due to their impact on acetylcholine, a neurotransmitter critical for memory.

Benzodiazepines: Associated with memory problems and increased dementia risk, potentially due to their sedative effects on the brain.

Proton Pump Inhibitors (PPIs): Long-term use may increase dementia risk by affecting brain health.

Statins: Some studies suggest a potential link to cognitive decline, though evidence is mixed.

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Non-steroidal anti-inflammatory drugs (NSAIDs): Linked to increased dementia risk due to their impact on brain inflammation.

Antihistamines (first-generation): Known to cause memory problems and potentially increase dementia risk by crossing the blood-brain barrier.

Antipsychotics: Increased dementia risk, particularly in elderly patients, due to their potent effects on brain function.

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